Dichloromethane
Product identifier
- Product name: Dichloromethane
- CBnumber: CB7740372
- CAS: 75-09-2
- EINECS Number: 200-838-9
- Synonyms: DCM,dichloromethane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Dichloromethane
- Synonyms: DCM,dichloromethane
- CAS: 75-09-2
- EC number: 200-838-9
- MF: CH2Cl2
- MW: 84.93
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Hydrogen chloride gas Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb? ). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Heat sensitive. Handle and store under inert gas.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Splash contact
Material: Fluorinated rubber Minimum layer thickness: 0,7 mm Break through time: 148 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
protective clothing
Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odourether-like
- Odour Threshold250 ppm
- pHNo data available
- Melting point/freezing pointMelting point/range: -97 °C
- Initial boiling point and boiling range39,8 - 40 °C
- Flash point- closed cupdoes not flash
- Evaporation rate0,71
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 22 %(V) Lower explosion limit: 13 %(V)
- Vapour pressure 584 hPa at 25 °C
- Vapour density 2,93
- Relative density1.329 (20/20℃)
- Water solubility13,2 g/l at 25 °C
- Partition coefficient: n-octanol/waterlog Pow: 1,25 at 20 °C - Bioaccumulation is not expected.
- Autoignition temperature605 °C at 1.013 hPa - DIN 51794
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 0,42 mPa.s at 25 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant2.49 at 30 °C (headspace-GC, Sanz et al., 1997)
- λmaxλ: 235 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 250 nm Amax: 0.05
λ: 260 nm Amax: 0.02
λ: 340-400 nm Amax: 0.01
Other safety information
Relative vapor density
2,93
Reactivity
No data available
Chemical stability
Sensitivity to light
The product is chemically stable under standard ambient conditions (room temperature) . Contains the following stabilizer(s):
2-methyl-2-butene (>0,005 - <0,015 %)
Possibility of hazardous reactions
Risk of explosion with:
Alkali metals nitrogen oxides nitrogen dioxide Potassium sodium azide perchloric acid Nitric acid
aluminium chloride Amines
Oxygen
(as liquefied gas) powdered aluminium sodium
aromatic hydrocarbons with
powdered aluminium Exothermic reaction with: Alkaline earth metals Powdered metals
amides alcoholates nonmetallic oxides
potassium tert-butanolate sodium amide
Lithium
Conditions to avoid
no information available
Incompatible materials
rubber, various plastics, Light metals, Metals, Mild steel
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicity(OECD Test Guideline 401)
LC50 Inhalation - Mouse - 4 h - 86 mg/l Remarks: (ECHA)
Symptoms: Possible damages:, mucosal irritations LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Result: Irritations - 4 h (OECD Test Guideline 404)
Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Risk of corneal clouding.
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: positive
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: positive
Test Type: In vivo micronucleus test Species: Mouse
Cell type: Bone marrow Application Route: Oral
Method: OECD Test Guideline 474 Result: negative
Toxicity
Remarks: (ECHA)
static test LC50 - Daphnia magna (Water flea) - 27 mg/l - 48 h (US-EPA)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 68 % - Readily biodegradable. (OECD Test Guideline 301D)
Bioaccumulative potential
Bioaccumulation Cyprinus carpio (Carp) - 6 Weeks
-
250 μg/l(Dichloromethane)
Bioconcentration factor (BCF): 2 - 5,4 (OECD Test Guideline 305)
Cyprinus carpio (Carp) - 6 Weeks
-
25 μg/l(Dichloromethane)
Bioconcentration factor (BCF): 6 - 40 (OECD Test Guideline 305)
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Incompatible with strong oxidizers, caustics; chemically active metals, such as aluminum, magnesium powders; potassium, lithium, and sodium; concentrated nitric acid causing fire and explosion hazard. Contact with hot surfaces or flames causes decomposition producing fumes of hydrogen chloride and phosgene gas. Attacks some forms of plastics, rubber and coatings.
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to regulations governing storage, transportation, treatment, and waste disposal. Incineration, preferably after mixing with another combustible fuel; care must be exercised to assure complete combustion to prevent the formation of phosgene.
UN number
ADR/RID: 1593 IMDG: 1593 IATA: 1593
UN proper shipping name
| | ADR/RID: DICHLOROMETHANE IMDG: DICHLOROMETHANE | |
| IATA: Dichloromethane | ||
| 14.3 | Transport hazard class(es) ADR/RID: 6.1 IMDG: 6.1 | IATA: 6.1 |
| 14.4 | Packaging group ADR/RID: III IMDG: III | IATA: III |
| 14.5 | Environmental hazards ADR/RID: no IMDG Marine pollutant: no | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.