2-CHLORO-N-(2-METHYLPHENYL)ACETAMIDE synthesis
- Product Name:2-CHLORO-N-(2-METHYLPHENYL)ACETAMIDE
- CAS Number:37394-93-7
- Molecular formula:C9H10ClNO
- Molecular Weight:183.63
95-53-4
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$10.00/1g
37394-93-7
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$33.39/1g
Yield: 90%
Steps:
18.A 2-chloro-N-(2-methylphenyl)acetamide
EXAMPLE 18A 2-chloro-N-(2-methylphenyl)acetamide The procedure described in Example 16A was followed, substituting 2-methylaniline for 3,5-dimethylaniline to provide the title compound (90% yield) as a white solid. 1H NMR (300 MHz, DMSO-d6) δ2.20 (s, 3H), 4.30 (s, 2H), 7.16 (m, 3H), 7.38 (d, 1H, J=7.8 Hz), 9.63 (br s, 1H); MS (DCI/NH3) m/e 184 (M+H)+.
References:
Bhatia, Pramila A.;Daanen, Jerome F.;Hakeem, Ahmed A.;Kolasa, Teodozyj;Matulenko, Mark A.;Mortell, Kathleen H.;Patel, Meena V.;Stewart, Andrew O.;Wang, Xueqing;Xia, Zhiren;Zhang, Henry Q. US2004/29887, 2004, A1
