3-(3-CHLOROPHENYL)CYCLOPENTANONE synthesis
1synthesis methods
- Product Name:3-(3-CHLOROPHENYL)CYCLOPENTANONE
- CAS Number:635682-02-9
- Molecular formula:C11H11ClO
- Molecular Weight:194.66
Yield:635682-02-9 83%
Reaction Conditions:
with chlorobis(ethylene)rhodium(I) dimer;(S)-(E)-2-(2-(3,4-dimethoxystyryl)phenyl)-4-benzyloxazoline;water;potassium hydroxide in 1,4-dioxane at 40;Inert atmosphere;optical yield given as %ee;enantioselective reaction;
References:
Hahn, Bjoern T.;Tewes, Friederike;Froehlich, Roland;Glorius, Frank [Angewandte Chemie - International Edition,2010,vol. 49,# 6,p. 1143 - 1146] Location in patent:supporting information; experimental part