3-(Trifluoromethyl)benzoic acid synthesis
- Product Name:3-(Trifluoromethyl)benzoic acid
- CAS Number:454-92-2
- Molecular formula:C8H5F3O2
- Molecular Weight:190.12
454-89-7
371 suppliers
$14.00/25g
454-92-2
362 suppliers
$5.00/5g
Yield:454-92-2 99%
Reaction Conditions:
with diphenyl diselenide;dihydrogen peroxide in water at 20; for 6 h;Green chemistry;
Steps:
3.2. General Procedure for the Synthesis of Carboxylic Acids 2
General procedure: Diphenyl diselenide (3, 0.006 g; 0.02 mmol) was treated with H2O2 (30%·w/w, 0.1 mL, 1 mmol) andwater (0.2 mL) and stirred at room temperature at 800 rpm until the discoloration of the reaction mixture;then, the aldehyde 1 (1 mmol) was added. After 6 h, the aqueous mixture was extracted three times withEtOAc (3 × 20 mL). The collected organic layers were dried over Na2SO4 and the solvent evaporatedunder reduced pressure.
References:
Sancineto, Luca;Tidei, Caterina;Bagnoli, Luana;Marini, Francesca;Lenardo, Eder J.;Santi, Claudio [Molecules,2015,vol. 20,# 6,p. 10496 - 10510]
349-75-7
239 suppliers
$9.00/5g
454-92-2
362 suppliers
$5.00/5g
401-78-5
393 suppliers
$5.00/5g
201230-82-2
1 suppliers
inquiry
2557-13-3
242 suppliers
$6.00/5g
454-92-2
362 suppliers
$5.00/5g
124-38-9
122 suppliers
$175.00/23402
401-81-0
238 suppliers
$10.00/10 g
454-92-2
362 suppliers
$5.00/5g
328-99-4
33 suppliers
$88.35/1gm:
454-92-2
362 suppliers
$5.00/5g