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ChemicalBook CAS DataBase List 4-Bromomethylbenzoic acid

4-Bromomethylbenzoic acid synthesis

12synthesis methods
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Yield:6232-88-8 90%

Reaction Conditions:

with sodium bromate;sodium hydrogensulfite in water;ethyl acetate

Steps:

1.1 Step 1
p-Toluic acid was treated with sodium bromate and sodium bisulfite in ethyl acetate and water to obtain p-bromomethylbenzoic acid in 90% yield (step 1).

References:

CHANNEL THERAPEUTICS, INC.;RAMANUJACHARY, Kandalam, V.;SUMAN, Pathi;PEREZ, Lark, J.;JONNALAGADDA, Subash, C. WO2019/60809, 2019, A1 Location in patent:Paragraph 0125

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