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ChemicalBook CAS DataBase List 6-Methoxyquinoline-4-carbaldehyde

6-Methoxyquinoline-4-carbaldehyde synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: phosphorus tribromide / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
2.1: n-butyllithium / diethyl ether / -78 °C
2.2: 3 h / -78 °C

References:

Tukulula, Matshawandile;Little, Susan;Gut, Jiri;Rosenthal, Philip J.;Wan, Baojie;Franzblau, Scott G.;Chibale, Kelly [European Journal of Medicinal Chemistry,2012,vol. 57,p. 259 - 267]

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