ChemicalBook CAS DataBase List ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate synthesis

4synthesis methods

Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS Number:874638-80-9
Molecular formula:C20H17FO6
Molecular Weight:372.35

D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester

93635-76-8
147 suppliers
$10.00/5g

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

874638-80-9
332 suppliers
$5.00/1g

Yield:-

Steps:

Multi-step reaction with 4 steps
1: sulfur(VI) fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine trishydrofluoride / acetonitrile / 5 h / -15 - 90 °C
2: 2,2-dimethoxy-propane; hydrogenchloride; lithium hydroxide monohydrate / tetrahydrofuran / 3 h / 20 °C
3: hydrogenchloride; lithium hydroxide monohydrate / ethanol / 21 h / 20 °C
4: pyridine / 0.5 h / 20 °C / Cooling with ice

References:

US2013/72699,2013,A1

879551-01-6 Synthesis

(4S,5R)-ethyl 5-((R)-2,2-diMethyl-1,3-dioxolan-4-yl)-4-Methyl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide

879551-01-6
12 suppliers
inquiry

874638-80-9
332 suppliers
$5.00/1g

References

98-88-4 Synthesis

98-88-4
569 suppliers
$10.00/5g

874638-80-9
332 suppliers
$5.00/1g

References

(S,E)-ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylacrylate

130606-67-6
3 suppliers
inquiry

874638-80-9
332 suppliers
$5.00/1g

References

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Related Search:

Sofosbuvir 2'-deoxy-2'-fluoro-2'-C-methyluridine PSI-6130 derivative Sofosbuvir Impurity13 1,3,5-Tri-O-benzoyl-D-ribofuranose Sofosbuvir metabolites GS566500 (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-bis(4-chlorobenzoate)