ChemicalBook >> CAS DataBase List >>((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate structure

CAS No.: 874638-80-9

Chemical Name:: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

Synonyms: (2R)-2-DEOXY-2-FLUORO-2-METHYL-D-ERYTHRO;((2R,3S,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;SFBM;SF-X1;Sofosbuvir INT 3;Sofosbuvir imp-2;PSI-6130 interMediate;Sofosbuvir Impurity 30;SofosBuvir Impurity 46

CBNumber:: CB32514087

Molecular Formula:: C20H17FO6

Molecular Weight:: 372.35

MDL Number:: MFCD17677380

MOL File:: 874638-80-9.mol

Last updated:2024-03-13 09:08:22

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((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Properties

Melting point	133℃
Boiling point	458.6±34.0 °C(Predicted)
Density	1.33
storage temp.	2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D232985	(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonicAcidγ-Lactone3,5-Dibenzoate	874638-80-9	25g	$165	2021-12-16	Buy
TRC	D232985	(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonicAcidγ-Lactone3,5-Dibenzoate	874638-80-9	50g	$275	2021-12-16	Buy
Usbiological	293138	3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone	874638-80-9	2g	$319	2021-12-16	Buy
Biosynth Carbosynth	MD09387	3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone	874638-80-9	100g	$410	2021-12-16	Buy
SynQuest Laboratories	2H23-3-13	((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate	874638-80-9	100g	$295	2021-12-16	Buy

Product number	Packaging	Price	Buy
D232985	25g	$165	Buy
D232985	50g	$275	Buy
293138	2g	$319	Buy
MD09387	100g	$410	Buy
2H23-3-13	100g	$295	Buy

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Chemical Properties,Uses,Production

Uses

(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1''-C-cyano-2''-fluoro-2''-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.

Uses

neuromuscular blocking agent

Application

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate is an impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate synthesis

Synthesis of ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate from D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Preparation Products And Raw materials

Raw materials

D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one Benzoyl chloride

Preparation Products

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Suppliers

Global( 306)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
JIANGXI TIME PHARMACEUTICAL CO.,LTD	+86-0794-7183888 +86-13155888520	sales@groupchem.com	China	27	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15962	58
Nanjing Gold Pharmaceutical Technology Co. Ltd.	025-84209270 15906146951		CHINA	115	55
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	724	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60

Supplier	Advantage
NewCan Biotech Limited	58
JIANGXI TIME PHARMACEUTICAL CO.,LTD	58
Henan Bao Enluo International TradeCo.，LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Nanjing Gold Pharmaceutical Technology Co. Ltd.	55
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Chembon Pharmaceutical Co., Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60

View Lastest Price from ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-18	((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 874638-80-9	US $10.00 / kg	1kg	99%	500t/month	Henan Bao Enluo International TradeCo.，LTD
2023-03-11	((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 874638-80-9	US $0.00 / kg	1kg	98.0%min	1000kg	LY Global chemicals co.,ltd .
2022-10-18	((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 874638-80-9	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
874638-80-9
US $10.00 / kg
99%
Henan Bao Enluo International TradeCo.，LTD

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
874638-80-9
US $0.00 / kg
98.0%min
LY Global chemicals co.,ltd .

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
874638-80-9
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Spectrum

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate(874638-80-9)¹HNMR

874638-80-9(((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate)Related Search:

D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) Sofosbuvir Impurity 17 L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester L-Alanine isopropyl ester hydrochloride (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate PSI-6130 derivative D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester

2'-deoxy-2'-fluoro-2'-C-methyluridine Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate sofosBuvir impurity 36 SofosBuvir Impurity 55

Sofosbuvir impurity E SofosBuvir Impurity 40 SofosBuvir Impurity 54

1of4

3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribono-γ-latone SFBM (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid γ-lactone 3,5-dibenzoate Sofosbuvir intermediate Sofosbuvir Impurity 30 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone (2R,3R,4R)-2-[(benzoyloxy)methyl]-4-fluoro-4-methyl-5-oxooxolan-3-yl benzoate Sofosbuvir Intermediate 1 Sofosbuvir INT 3 ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-dibenzoate Methyl ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl) benzoate (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate PSI-6130 interMediate ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-C-Methyl-D-ribono-γ-lactone D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-Methyl-, γ-lactone, 3,5-dibenzoate, (2R)- (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythropentonic acid InterMediate of Sofosbuvir 3. ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetra (2R)-2-Deoxy-2-fluoro-2-methy-D- erythropentonic acid gamma-lactone 3,5- dibenzoate nterMediate of Sofosbuvir Di-O-benzoyl-2-deoxy-2-fluoro-2-C-Methyl-D Sofosbuvir imp-2 3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-C-methyl-D-ribono-γ-latone 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one SofosBuvir Impurity 46 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-arabino-1,4-lactone (2R-3R,4R)-3-(Benzoyzxy)-4-Fluoro-4-Methyl-5-Oxotetrahydrofuran-2Yl)Methyl Benzoate Sofosbuvir Impurity 101 ((2R,3R,4R)-3-(BENZOYLOXY)-4-FLUORO-4-METHYL-5-OXOTETRAHYDROFURAN-2-YL)METHYL BENZOATE 874638-80-9 SF-X1 ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate ISO 9001：2015 REACH ((2R,3R,4R)-3-(DENZOYLOXY)-4-FLUORO-4-METHYL-5-OXOTETRAHYDROFURAN-2-YL)METHYL BENZOATE ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydro... ((2R,3S,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate (2R)-2-DEOXY-2-FLUORO-2-METHYL-D-ERYTHRO (S)-isopropyl 2-(((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate (2R,3R,4R)-3- (benzoyoxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2yl)methyl Benzoate, 98% (2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-D-ribono-r-lactone 874638-80-9 1334518-02-8 874638-08-9 C20H17FO6 C20H17O6F apis Sofosbuvir intermediate