ChemicalBook CAS DataBase List DIETHYL 4-METHOXYPHENYL MALONATE

DIETHYL 4-METHOXYPHENYL MALONATE synthesis

12synthesis methods

Product Name:DIETHYL 4-METHOXYPHENYL MALONATE
CAS Number:23197-67-3
Molecular formula:C14H18O5
Molecular Weight:266.29

104-01-8 Synthesis

104-01-8
513 suppliers
$6.00/10g

23197-67-3
24 suppliers
$24.00/250 mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 96 percent / conc. HCl / Heating
2: 75 percent / NaH / hexane; tetrahydrofuran / 60 °C

References:

Matulenko, Mark A.;Paight, Ernest S.;Frey, Robin R.;Gomtsyan, Arthur;DiDomenico Jr., Stanley;Jiang, Meiqun;Lee, Chih-Hung;Stewart, Andrew O.;Yu, Haixia;Kohlhaas, Kathy L.;Alexander, Karen M.;McGaraughty, Steve;Mikusa, Joseph;Marsh, Kennan C.;Muchmore, Steven W.;Jakob, Clarissa L.;Kowaluk, Elizabeth A.;Jarvis, Michael F.;Bhagwat, Shripad S. [Bioorganic and Medicinal Chemistry,2007,vol. 15,# 4,p. 1586 - 1605]

104-92-7 Synthesis