ISOPROPENYLMAGNESIUM BROMIDE synthesis

Yield:-

Reaction Conditions:

with magnesium in tetrahydrofuran

Steps:

26.a a)
a) isopropenylmagnesium bromide To a mixture of magnesium (turnings, 6.33 g) and tetrahydrofuran (20 ml) was added dropwise 10 ml of a solution of 2-bromopropene (20 ml) in tetrahydrofuran (230 ml) under an argon atmosphere with heating. After the reaction was started, the remaining solution was dropwise added at a rate that maintained refluxing. The mixture was refluxed for 1 hr, and cooled to room temperature to give a solution (0.82 M) of the title compound in tetrahydrofuran.

References:

Japan Tobacco Inc. EP885869, 1998, A1

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