MK8245 synthesis
- Product Name:MK8245
- CAS Number:1030612-90-8
- Molecular formula:C17H16BrFN6O4
- Molecular Weight:467.25
5382-16-1
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1030612-90-8
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$48.00/2mg
Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: potassium tert-butylate / tetrahydrofuran / 0.42 h / Reflux; Inert atmosphere; Large scale reaction
1.2: 1.92 h / Reflux; Inert atmosphere; Large scale reaction
2.1: 18 h / 135 °C / neat (no solvent)
3.1: triethylamine / tetrahydrofuran; 2-methyltetrahydrofuran / 2.83 h / 55 - 58 °C / Inert atmosphere; Large scale reaction
4.1: formic acid / 2 h / 95 °C / Inert atmosphere; Large scale reaction
References:
Girardin, Melina;Dolman, Sarah J.;Lauzon, Sophie;Ouellet, Stephane G.;Hughes, Greg;O'Shea, Paul D.;Fernandez, Paul;Zhou, George [Organic process research and development,2011,vol. 15,# 5,p. 1073 - 1080]
1000210-73-0
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1030612-90-8
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1329632-66-7
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916971-27-2
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1030612-90-8
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348-57-2
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$5.00/5g
1030612-90-8
81 suppliers
$48.00/2mg