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ChemicalBook CAS DataBase List Vanoxerine dihydrochloride

Vanoxerine dihydrochloride synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: acetonitrile / 8 h / 75 - 80 °C / Large scale
2: hydrogenchloride / ethanol / 2 h / 20 - 30 °C / Large scale
3: sodium carbonate / water; butanone / 24 h / 75 - 80 °C / Large scale
4: hydrogenchloride / ethanol / 2 h / 15 - 25 °C / Large scale

References:

Ironside, Michael D.;Sugathapala, Priyantha M.;Robertson, Jerod;Darey, Mark C.P.;Zhang, Jianzhong [Organic Process Research and Development,2002,vol. 6,# 5,p. 621 - 627]

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