Methionine synthesis and Methionine benefits

Methionine is an essential amino acid found in meat, fish, and dairy products. It is an amino acid that is used to build molecules important for cell and DNA function.

Health benefits

Amino acids help build the proteins that make up the tissues and organs of your body.

In addition to this critical function, some amino acids have other special roles.

Methionine is an amino acid that is used to produce several important molecules in your body. These molecules are essential for the proper functioning of your cells.

Methionine synthesis

As an essential amino acid, methionine is not synthesized de novo in humans and other animals, which must ingest methionine or methionine-containing proteins. In plants and microorganisms, methionine biosynthesis belongs to the aspartate family, along with threonine and lysine (via diaminopimelate, but not via α-aminoadipate). The main backbone is derived from aspartic acid, while the sulfur may come from cysteine, methanethiol, or hydrogen sulfide.

Catabolism

Methionine is converted to S-adenosylmethionine (SAM-e) by methionine adenosyltransferase.

SAM-e serves as a methyl donor in many methyltransferase reactions, and is converted to S-adenosylhomocysteine (SAH).

Adenosylhomocysteinase cysteine.

Recommended intake

Amino acids (AAs) can be taken as single AAs. Or in AA combinations. They also come as part of multivitamins, proteins, and food supplements. The forms include tablets, fluids, and powders.

You get all of the amino acids you need if you eat enough protein in your diet.

Side Effects

Methionine is commonly consumed in foods. It is possibly safe when used as medicine under the supervision of a healthcare provider. But methionine is possibly unsafe when used for self-medication. Too much methionine can cause brain damage and death. Methionine can increase blood levels of homocysteine, a chemical that may cause heart disease, and might also promote the growth of some tumors.