Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
Methyl 3,4,5-Trimethoxybenzoate: A Versatile Molecule as Membrane-Active Anticancer Agents
Methyl 3,4,5-trimethoxybenzoate interacts strongly with cell membranes, demonstrating potent antiproliferative activity against cancer cells.
Sep 30,2025 API4-Chlorodehydromethyltestosterone: From Development and Abuse to Advanced Detection Strategies
4-Chlorodehydromethyltestosterone is a banned steroid with a complex metabolism and detection strategies using GC-MS/MS have identified long-term metabolites.
Sep 30,2025 APIRepotrectinib: A New Anti-cancer Drug
Repotrectinib is an oral inhibitor of ROS1, and it represents the first approved targeted therapy that specifically includes patients previously treated with a ROS1 TKI in FDA labeling.
Sep 29,2025 APIA Comprehensive Analysis of Magnolol
This work details magnolol's diverse bioactivities, glucuronidation metabolism, solubility/bioavailability solutions, and safe use via toxicological studies.
Sep 26,2025 APIOleuropein: Health Benefits and Role in Preventing Non-Communicable Diseases
Oleuropein aids glucose metabolism/insulin sensitivity, has antioxidant/anti-inflammatory traits, and helps prevent non-communicable diseases.
Sep 26,2025 APIFluoxymesterone: Clinical Uses and Molecular Interactions
Fluoxymesterone treats low testosterone/delayed puberty/breast cancer; it aids Tam in AR-enriched breast cancer and inhibits human 11β-HSD2.
Sep 26,2025 APIDoxofylline: Efficacy/Safety in COPD and Superiority to Theophylline
Doxofylline treats/prevents asthma/COPD via bronchodilation/anti-inflammation, has better safety than theophylline, and needs no routine plasma monitoring.
Sep 25,2025 API1-Naphthylboronic Acid: Basic Properties and Applications
1-Naphthylboronic Acid is a key reagent for polycyclic aromatics prep, enabling Suzuki-Miyaura-catalyzed enantioselective synthesis of axially chiral biaryls.
Sep 24,2025 API4-Formylmorpholine: Vapor-Liquid Equilibrium and Extractive Distillation Application
4-Formylmorpholine (solvent) has VLE data with toluene/xylenes/3-methylthiophene measured; supporting its extractive distillation use.
Sep 23,2025 APIPolyquaternium-2: Applications in Cosmetics and as a Levelling Agent for Copper Electroplating
Polyquaternium-2 acts as a cosmetic additive and effective levelling agent for copper electroplating, enhancing TH plating performance via surface adsorption.
Sep 22,2025 API