Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
Avatrombopag: mechanism of action, pharmacokinetics and clinical applications
Avatrombopag is a medication that treats thrombocytopenia by mimicking thrombopoietin, increasing platelet count through receptor activation and signal pathways.
Sep 26,2023 APIPyridine-4-boronic acid: properties, applications and safety
Pyridine-4-boronic acid is a versatile compound with unique properties, used in various organic chemistry applications and drug discovery.
Sep 26,2023 APICannabidiol: pharmacology, clinical applications and toxicity
Cannabidiol is a non-psychoactive compound from cannabis, effective in treating epilepsy, chronic pain, and anxiety.
Sep 26,2023 API1-Phenyl-2-nitropropene: properties, applications and safety
1-Phenyl-2-nitropropene is a versatile compound with potential applications in organic synthesis and medicine, but requires careful handling and storage due to its harmful and irritant effects.
Sep 26,2023 APINeomycin sulfate:uses and detection
Neomycin sulfate is a commonly used antibiotic but is toxic to environmental life and human health, so it is important to detect the concentration of Neomycin sulfate in living organisms and water res
Sep 25,2023 API4-Formylbenzoic acid: applications and safety
4-Formylbenzoic acid is a versatile compound used in sugar sensing, antibacterial research, and enzymatic studies, requiring careful handling for safety.
Sep 25,2023 API2,2'-Dithiobis(benzothiazole): properties, applications and toxicity
2,2'-Dithiobis(benzothiazole) is a versatile compound with diverse applications including rubber industry and chemical synthesis.
Sep 25,2023 APIBenzoyl peroxide: a widely used organic acid
Benzoyl peroxide is an organic acid with widely used
Sep 22,2023 APIAntioxidant 245: properties, applications and safety
Antioxidant 245 is a versatile chemical with excellent antioxidant properties, used for long-term thermal stabilization and enhancing durability in various industries.
Sep 22,2023 API