Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
Pramoxine hydrochloride: mechanism of action, clinical applications and safety
Pramoxine hydrochloride is a safe and effective topical medication for temporary relief of pain and itching associated with various dermatological conditions.
Oct 24,2023 APIBrominated polystyrene: properties, applications and safety
Brominated polystyrene is a versatile material with exceptional properties, but safety considerations and compliance with regulations are crucial.
Oct 24,2023 API2-Thiouracil: properties, applications and safety
2-Thiouracil has diverse applications in pharmaceutical synthesis, biochemical research, and materials science, but its potential carcinogenicity necessitates strict safety measures.
Oct 24,2023 APIChlorambucil: mechanism of action, clinical applications and hepatotoxicity
Chlorambucil is an effective alkylating agent used in cancer treatment, targeting DNA replication and inducing apoptosis.
Oct 23,2023 APIS-Acetyl-L-glutathione: activities and applications
S-Acetyl-L-glutathione is a promising compound that has demonstrated potential in inducing lymphoma cell apoptosis, improving liver function, and supporting overall health.
Oct 23,2023 APIWhat is 17-AAG?
17-AAG is an Hsp90 inhibitor. This compound is a synthetic analog of geldanamycin, an antibiotic first purified in 1970 from Streptomyces hygroscopicus.
Oct 20,2023 API5-Fluorocytosine:Introduction and Indication
5-Fluorocytosine is clinically licensed for the treatment of cryptococcosis, chromoblastomycosis, and aspergillosis.
Oct 20,2023 API2,3,5-Tri-O-benzyl-D-ribonolactone: applications in organic synthesis and safety
2,3,5-Tri-O-benzyl-D-ribonolactone is a key compound in the synthesis of important drugs, but requires careful handling due to its acute toxicity.
Oct 20,2023 APIPhenylmethylsulfonyl fluoride: activities and applications
Phenylmethylsulfonyl fluoride is a potent inhibitor of proteases and esterases, widely used in research for sample preservation and protein purification.
Oct 20,2023 APIAntioxidant 565: properties, applications and safety
Antioxidant 565 is a versatile compound that exhibits strong antioxidant properties, with applications in various industries.
Oct 19,2023 API