Perampanel: A Promising AMPA Receptor Antagonist for Epilepsy Treatment
Perampanel is used alone or together with other medicines to treat certain types of epilepsy, such as partial onset seizures and generalized tonic-clonic seizures.
Nov 12，2024 API
Estradiol Valerate: Pharmacodynamic Effects, Pharmacokinetics and Dosage and Administration
Estradiol valerate (EV), sold for use by mouth under the brand name Progynova , is an estrogen medication.
Nov 12，2024 API
Btk Kinase Inhibitor: Pharmacodynamics, Pharmacokinetics and Adverse Events
Btk Kinase Inhibitor, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, exerts its pharmacodynamics through irreversible covalent binding to BTK Cys-481.
Nov 12，2024 API
Bovine serum albumin: A generalist in Biochemistry
BSA is described as a globular non-glycoprotein with a molecular weight close to 66 430. It is made of 583 amino acid residues and has 17 cystine residues (8 disulphides bridges and 1 free thiol group
Nov 11，2024 Biochemical Engineering
Disodium Phosphate: A Comprehensive Overview
Disodium phosphate is a widely used derivative product of phosphoric acid. Disodium phosphate is used directly in water treatment for corrosion control or blended with polyphosphates for corrosion con
Nov 11，2024 API
Ginkgolide B: Origin, Pharmacokinetics and Neuroprotective Effects
Ginkgolide B from Ginkgo biloba offers neuroprotection by reducing infarct size, enhancing survival, and modulating cellular pathways in ischemic strokes.
Nov 11，2024 Natural Products
3-Butenenitrile: Occurrence, Metabolism and Health Effects
3-Butenenitrile plays a key role in industry and surgery, with potential health impacts. Subtoxic exposure may enhance enzyme activities, offering protective effects.
Nov 11，2024 API
Nicotinic Acid: Mechanism of Action, Effect on Lipid Profile and Cardiovascular Risk
Nicotinic acid improves lipid profiles via GPR109A activation, apoB degradation, and CETP activity modulation, yet its efficacy combined with statins warrants further investigation.
Nov 11，2024 API
Phosphorus oxychloride:Reactions with water,Uses,Hazards and Warnings
Phosphorus oxychloride is a colourless liquid with the formula POCl3.
Nov 11，2024 Organic reagents
Why is febuxostat better than allopurinol?
The cardiovascular safety of febuxostat compared to allopurinol for treating gout remains equivocal. Febuxostat had a better safety outcome compared with allopurinol.
Nov 11，2024 API