Abiraterone: Therapeutic Target and Impact of Food on its Exposure
Abiraterone targets CYP17A in CRPC, disrupting androgen synthesis. It inhibits unintended AR targets and requires fasting for optimal efficacy.
Feb 22,2024 API2-Aminothiazole: structural characteristics and its derivatives as anti-cancer agents
2-Aminothiazole derivatives hold promise as anti-cancer agents due to versatile modifications, tubulin inhibition, and histone modulation.
Feb 22,2024 API3-Mercapto-1,2-propanediol: Properties, Applications in Sperm Cryopreservation, and Toxic Effects
3-Mercapto-1,2-propanediol is a versatile compound with physical and physiological properties used in various fields, including cryopreservation, but safety guidelines must be followed.
Feb 22,2024 APITriethylene Glycol Dimethacrylate: Properties and Induction of Apoptotic Proteins in Pulp Fibroblasts
Triethylene glycol dimethacrylate in composites causes apoptotic cell death in fibroblasts, impacting pulp tissue. Control and prevention strategies are crucial in dental applications.
Feb 22,2024 API2-Chlorotoluene: Overview and Degradation by Rhodococcus sp.
Rhodococcus sp. OCT 10 effectively degrades 2-Chlorotoluene, preventing harmful by-products and offering potential for bioremediation applications.
Feb 22,2024 APIHow to synthesis Cyhalodiamide?
The action mode of cyhalodiamide relies on activating the ryanodine receptors (RyRs) and affecting the release of calcium, leading to feeding cessation, emesis, hunger, dehydration, and terminal death
Feb 21,2024 Chemical pesticides The introduction of Tetrachlorantraniliprole
Tetrachlorantraniliprole (TCAP) is a novel anthranilic diamide insecticide targeting the ryanodine receptors of lepidopteran insect species with excellent insecticidal activity.
Feb 21,2024 Chemical pesticides An isoxazoline insecticide- Fluxametamide
Fluxametamide was announced by Nissan Chemical Industries as a new insecticide in 2015.
Feb 21,2024 Chemical pesticides 2-(2-Chlorophenyl)-2-nitrocyclohexanone: Overview, Side Effects and Dosage
Follow medical guidance for safe application of 2-(2-Chlorophenyl)-2-nitrocyclohexanone cream to treat fungal skin infections and minimize side effects.
Feb 21,2024 APIStanolone: Pharmacology, Clinical Applications and Analytical Methods
Stanolone is a synthetic androgen hormone with anabolic effects used in breast cancer treatment, caution needed for side effects, LC-MS/MS for accurate serum measurement.
Feb 21,2024 API