Avatrombopag Maleate: Preclinical Pharmacology, Pharmacokinetics and Metabolism
Avatrombopag maleate shows potent TPO receptor activation, selective human platelet generation, and promising pharmacokinetics, supporting its development for platelet disorders.
Mar 28，2024 API
1,5-Naphthalene diisocyanate: Preparation, Applications as a Building Block and Health Hazards
1,5-Naphthalene diisocyanate is prepared with high yield, serving as a crucial building block for high-performance polyurethane elastomers, yet posing significant health hazards.
Mar 28，2024 API
Minoxidil sulphate: History and Pharmacokinetics
Minoxidil sulphate, approved for hypertension, later found use in treating baldness due to hypertrichosis. Its absorption and metabolism inform treatment optimization.
Mar 28，2024 API
The refinement of the crystal structure of skutterudite, CoAs3
The crystal structure of skutterudite, cobalt triarsenide, has been re-refined with new data collected at 22 °C on a Picker automatic diffractometer (Mo Ke) out to a maximum sin 0/).=0.60, with the mo
Mar 27，2024 API
Regorafenib: Uses, Mechanism of Action and Side effects
Regorafenib is a targeted anticancer prescription drug that belongs to the diphenylurea class of multikinase inhibitors, targeting angiogenic receptors (VEGFR1-3, TIE2), stromal receptors (PDGFR-β, FG
Mar 27，2024 Drugs
Uranium diboride:Crystal structure,Uses,Synthesis
Uranium diboride (UB2) is a refractory ceramic with physical properties that make it a promising candidate for the development of high-performance nuclear materials, including fuel.
Mar 27，2024 Inorganic chemistry
Uses and Features of Chromium nitride
Chromium nitride is very hard and is extremely resistant to corrosion. It is an interstitial compound, with nitrogen atoms occupying the octahedral holes in the chromium lattice.
Mar 27，2024 Inorganic chemistry
Gadolinium oxide: Single crystals and Structural motifs for diferent phases
Structural motifs for diferent phases of Gd2O3. a–d Hexagonal, monoclinic, cubic and tetragonal phases, respectively. The pink and red spheres indicate gadolinium (Gd) and oxygen (O) atoms, respective
Mar 27，2024 API
The introduction of 3,4-Dimethoxybenzoic acid (Veratric acid)
Veratric acid (VA; 3,4-Dimethoxybenzoic acid) is a natural compound isolated from Sparassis crispa (cauliflower mushroom), which is an edible mushroom containing b-glucan that enhances anti-tumor resp
Mar 27，2024 Natural Products
What is the Crystal Structure of Bismuth Selenide?
Bismuth selenide (Bi2Se3) is one of the most popular representative candidates for three-dimensional TI suitable for electronic applications. This article will introduce the crystal structure of Bi2Se
Mar 27，2024 Inorganic chemistry