Abiraterone: Therapeutic Target and Impact of Food on its Exposure

Abiraterone targets CYP17A in CRPC, disrupting androgen synthesis. It inhibits unintended AR targets and requires fasting for optimal efficacy.

Feb 22,2024  API

2-Aminothiazole: structural characteristics and its derivatives as anti-cancer agents

2-Aminothiazole derivatives hold promise as anti-cancer agents due to versatile modifications, tubulin inhibition, and histone modulation.

Feb 22,2024  API

3-Mercapto-1,2-propanediol: Properties, Applications in Sperm Cryopreservation, and Toxic Effects

3-Mercapto-1,2-propanediol is a versatile compound with physical and physiological properties used in various fields, including cryopreservation, but safety guidelines must be followed.

Feb 22,2024  API

Triethylene Glycol Dimethacrylate: Properties and Induction of Apoptotic Proteins in Pulp Fibroblasts

Triethylene glycol dimethacrylate in composites causes apoptotic cell death in fibroblasts, impacting pulp tissue. Control and prevention strategies are crucial in dental applications.

Feb 22,2024  API

2-Chlorotoluene: Overview and Degradation by Rhodococcus sp.

Rhodococcus sp. OCT 10 effectively degrades 2-Chlorotoluene, preventing harmful by-products and offering potential for bioremediation applications.

Feb 22,2024  API

How to synthesis Cyhalodiamide?

The action mode of cyhalodiamide relies on activating the ryanodine receptors (RyRs) and affecting the release of calcium, leading to feeding cessation, emesis, hunger, dehydration, and terminal death

Feb 21,2024  Chemical pesticides ​

The introduction of Tetrachlorantraniliprole

Tetrachlorantraniliprole (TCAP) is a novel anthranilic diamide insecticide targeting the ryanodine receptors of lepidopteran insect species with excellent insecticidal activity.

Feb 21,2024  Chemical pesticides ​

An isoxazoline insecticide- Fluxametamide

Fluxametamide was announced by Nissan Chemical Industries as a new insecticide in 2015.

Feb 21,2024  Chemical pesticides ​

2-(2-Chlorophenyl)-2-nitrocyclohexanone: Overview, Side Effects and Dosage

Follow medical guidance for safe application of 2-(2-Chlorophenyl)-2-nitrocyclohexanone cream to treat fungal skin infections and minimize side effects.

Feb 21,2024  API

Stanolone: Pharmacology, Clinical Applications and Analytical Methods

Stanolone is a synthetic androgen hormone with anabolic effects used in breast cancer treatment, caution needed for side effects, LC-MS/MS for accurate serum measurement.

Feb 21,2024  API
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