A BRAF inhibitor: Encorafenib (LGX818)

Encorafenib (LGX818) is a BRAF inhibitor, and detection of a BRAF V600E or BRAF V600K mutation in tumor specimens is required before treatment.

Dec 27,2023  Inhibitors

Hyaluronic acid: Uses; Biological function; Side effects and Benefits

Hyaluronic acid (HA) is a natural substance found in the eyes, joints and skin. It acts as a cushion and lubricant in joints and other tissues.

Dec 27,2023  Biochemical Engineering

Is Fluorene nonpolar?

Fluorene is a polycyclic aromatic hydrocarbon that is commonly used in the manufacturing of OLEDs, dyes, and plasticizers.

Dec 27,2023  Organic Chemistry

A small-molecule inhibitor: IPI 145(Duvelisib)

Duvelisib (IPI 145) is a small-molecule inhibitor of phosphatidylinositol-3 kinase that has been developed as an oral treatment for various cancer indications.

Dec 27,2023  Inhibitors

Why is Pentane nonpolar?

Pentane is a natural product found in Calendula officinalis and Allium ampeloprasum.It appears as a clear colorless liquid with a petroleum-like odor. Less dense than water and insoluble in water. Hen

Dec 27,2023  Chemical Reagents

The Polar and Non-polar Characteristics in the Structure of Salicylic Acid

Salicylic acid has two polar regions, a carboxyl group and a hydroxyl group, but also has a non-polar 6 carbon hydrocarbon, which affect its boiling point and water solubility.

Dec 27,2023  API

Polarity of Benzaldehyde

Benzaldehyde (C6H5CHO) is an organic compound consisting of a benzene ring with a formyl substituent. It is the simplest aromatic aldehyde and one of the most industrially useful.

Dec 27,2023  Organic Chemistry

How to synthesize Dacomitinib (PF299804)?

Dacomitinib (PF299804), developed by Pfizer, is a second-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor.

Dec 27,2023  Inhibitors

Structure, Intermolecular Interactions and Applications of Enzaldehyde

Benzaldehyde represents the simplest aromatic aldehyde and the most used industrially. This article will introduce its structure, intermolecular interactions and applications.

Dec 27,2023  Organic Chemistry

The synthesis method of Binimetinib

Binimetinib is a non-ATP competitive mitogen-activated protein kinase 1/2 (MEK1/2) inhibitor discovered by Array BioPharma.

Dec 27,2023  Inhibitors
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