Belumosudil: Synthesis and Description
Belumosudil is an orally active Rho-associated coiled-coil-containing protein kinase-2 (ROCK2) inhibitor recently approved for chronic graft-versus-host disease (cGVHD) after failure of two prior line
Jan 17，2024 Inhibitors
What is the connection between TBTU and HBTU?
HBTU is a standard coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis.
Jan 17，2024 Biochemical Engineering
Ponesimod: Synthesis and Description
Ponesimod was approved in 2021 for the treatment of relapsing forms of multiple sclerosis (MS). This medication is an orally administered, selective sphingosine-
Jan 17，2024 Drugs
How is Difamilast synthesised?
Difamilast is synthesised in two steps by chemical reaction using the monobenzylated protocatechuic acid ethyl ester as a raw material.
Jan 17，2024 Inhibitors
Voclosporin: Synthesis and Description
Voclosporin is a calcineurin inhibitor immunosuppressant that received its first approval by the USFDA for the treatment of active lupus nephritis, making it the first oral therapy approved in the US
Jan 17，2024 Inhibitors
Tungsten carbide: General Properties; Industrial Preparation; Industrial Applications and Uses
Tungsten carbide can be used for a wide variety of applications. It has many applications that utilize its corrosion-resistant property such as wear plates, drawing dies, and wear parts for wire weari
Jan 16，2024 API
Titanium diboride: General Properties; Industrial Preparation and Processing; Industrial Applications and Uses
Titanium diboride was originally developed to make lightweight armor for US and Soviet army tanks. It also has many commercial applications such as nozzles, seals, cutting tools, dies, wear parts due
Jan 16，2024 API
The different Types of Fluoroelastomers
Fluoroelastomers combine excellent chemical resistance (e.g., oxidizing acids and alkalis) and high-temperature resistance.
Jan 16，2024 Catalyst and Auxiliary
Boron Carbide: General Properties; Industrial Preparation; Industrial Applications and Uses
The applications of boron carbide are as wear-resistant components. Armor tiles in military applications such as in light hard bulletproof armor for helicopters and tanks or as thermal shield for th
Jan 16，2024 API
A material with many uses: Natural rubber
Natural rubber has good dielectric properties, excellent resilience, an elevated damping capacity, and good tear resistance.
Jan 16，2024 Plant extracts