Pharmacodynamics and Toxicity of Flutrimazole
Flutrimazole is an imidazole derivative with the chemical name 1- [o-fluoro-a-(p-fluorophenyl)-a-phenylbenzyl]imidazole; the chemical structure is shown in Figure 148.1. Flutrimazole has a broad spect
Mar 29，2022 API
Mechanism of action of Cycloserine
Cycloserine was isolated by independent investigators in the early 1950s from cultures of Streptomyces orchidaceus and S. garyphalus. Racemic cycloserine can be synthesized but the active antibiotic,
Mar 29，2022 APIWhat is Posaconazole?
Posaconazole is a triazole drug which inhibits cytochrome P450- dependent C14-a sterol demethylase, a key enzyme in the biosynthesis of fungal ergosterol.
Mar 29，2022 Antipyretic analgesics
Mechanism of action of Capreomycin
Capreomycin is an important reserve antibiotic for the treatment of tuberculosis and has been used for this purpose for more than 40 years. It is a naturally produced cyclic polypeptide first isolated
Mar 29，2022 API
Mechanism of action of Thiacetazone
Thiacetazone (also called thioacetazone or amithiozone) was synthesized by Behnisch and Schmidt and investigated clinically by Gerhard Domagk and co-workers in Germany in the 1940s. It was subsequentl
Mar 29，2022 APIVoriconazole:azole drug
Voriconazole (Vfend, UK-109,496) is a synthetic triazole derivative with potent broad-spectrum activity. Its structure is similar to fluconazole, but one triazole ring is replaced with a fluorinated p
Mar 29，2022 API
Mechanism of action of Ethionamide
Ethionamide (2-ethyl-4-pyridinecarbothioamide) is a derivative of isonicotinic acid that was first synthesized in France in 1956 and quickly shown to be an effective anti-anti-tuberculosis agent. It i
Mar 29，2022 API
Side effects of Para-aminosalicylic acid
Para-aminosalicylic acid (PAS) was discovered as a result of a deliberate search for antituberculosis drugs. In 1941 Bernheim showed that salicylic and benzoic acids increase the oxygen consumption of
Mar 29，2022 API
The review of levodopa
Levodopa is a precursor drug of dopamine (DA), which has no pharmacological activity.
Mar 29，2022 API
Reaction of 1-Hexene
1-hexene is an organic compound with chemical formula C6H12. It is a colorless liquid, insoluble in water, soluble in ethanol
Mar 29，2022 API