Adverse effects of Adefovir dipivoxil
Adefovir dipivoxil is a white to off-white crystalline powder with an intrinsic aqueous solubility in water of 19 mg/ml at pH 2 and 0.4 mg/ml at pH 7.2.
Apr 6,2022 APIMechanism of action of Entecavir
Entecavir (BMS-200475) is a guanosine nucleoside analog with selective activity against hepatitis B virus (HBV), as well as some activity toward HIV. It is marketed as Baracludes, and received regulat
Apr 6,2022 APIUses and Side effects of Elvitegravir
Elvitegravir (brand name Vitekta) is a drug used as part of antiretroviral therapy (ART). The FDA approved elvitegravir in 2012 as an antiretroviral drug (ARV) for people with HIV infection. Elvitegra
Apr 2,2022 APISide effects of Maraviroc
Maraviroc was synthesized by Pfizer Inc as UK-427,857 (4, 4-difluoro- N-[(1S)-3-[exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[ 3.2.1]oct-8-yl]-1-phenylpropyl]cyclohexanecarboxamide)
Apr 2,2022 APISide effects of Enfuvirtide
Enfuvirtide is an antiretroviral drug used in salvage regimens in (usually) highly drug-experienced individuals that suppresses replication of HIV-1 strains with multidrug resistance to reverse transc
Apr 2,2022 APIMechanism of action of Tipranavir
Tipranavir (formerly known as PNU-140690) is the first of a new class of nonpeptide protease inhibitors, the dihydropyrone sulfonamides. Tipranavir was developed and is marketed by Boehringer Ingelhei
Apr 2,2022 APIUses and Side effects of Atazanavir
Atazanavir (ATV) sulfate, (3S,8S,9S,12S)-3,12-bis(1,1-dimethylethyl)- 8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl] methyl]-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester
Apr 2,2022 APIUses and Side effects of Darunavir
Darunavir is a synthetic nonpeptidic analog of amprenavir that functions as a human immunodeficiency virus (HIV) protease inhibitor. HIV protease cleaves gag-pol proteins in HIV-infected cells and thu
Apr 2,2022 APISide effects of Fosamprenavir
Fosamprenavir is a sulfa-containing calcium phosphate ester prodrug of amprenavir. Like other HIV-1 protease inhibitors, amprenavir binds to the active site of the HIV-1 protease. This prevents the pr
Apr 2,2022 APISide effects of Lopinavir
Lopinavir (formerly known as ABT-378) is an HIV-1-specific protease inhibitor engineered specifically to address the shortcomings of earlier agents in the protease inhibitor class.
Apr 1,2022 API