Cefotaxime: Antimicrobial Activity, Susceptibility, Administration and Dosage, Pharmacokinetics etc.
Cefotaxime is referred to as a third-generation or extended-spectrum cephalosporin. It was developed in the 1970s and was approved by the US Food and Drug Administration (FDA) in 1981 (Lo and Friedman
Mar 23,2022 APICefoperazone/sulbactam: Clinical Uses and Toxicity
Given that cefoperazone–sulbactam is the predominant formulation used at the present time, discussion regarding clinical uses will concentrate on this drug combination.
Mar 23,2022 APIApplication and Pharmacology of Benzoic acid
Benzoic acid appears as a white crystalline solid. Slightly soluble in water. The primary hazard is the potential for environmental damage if released.
Mar 23,2022 Food AdditivesApplication of Diethyl malonate
Pure diethyl malonate (DEM) is a colorless and transparent liquid with the aromatic odor of ether, and the industrial product is a light yellow transparent liquid, which is slightly soluble in water a
Mar 23,2022 Organic Synthesis IntermediateA nucleoside analogue:Molnupiravir
Molnupiravir(EIDD-2801) is a nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group.
Mar 23,2022 Pharmaceutical intermediatesCefoperazone: Antimicrobial Activity, Susceptibility, Administration and Dosage, Clinical Uses etc.
Cefoperazone is referred to as an extended-spectrum or thirdgeneration cephalosporin. It is stable to some beta-lactamases, particularly those produced by Gram-negative bacteria, and has potency agai
Mar 23,2022 APICefoxitin: Antimicrobial Activity, Susceptibility, Administration and Dosage, Clinical Uses etc.
Cephamycins A, B, and C are naturally occurring beta-lactam antibiotics that were obtained from several Streptomyces spp. at Merck Research Laboratories (Stapley et al., 1972). Cefotetan disodium, cef
Mar 23,2022 APICefotiam: Antimicrobial Activity, Susceptibility, Administration and Dosage, Clinical Uses etc.
Cefotiam is widely used as perioperative prophylaxis in Japan. It is predominantly used intravenously (in the form of cefotiam hydrochloride – C18H23N9O4S3 2HC1), although an oral formulation is av
Mar 23,2022 APIApplication of 2-Amino-5-chlorobenzophenone
2-amino-5-chlorobenzophenone crystal was grown using slow evaporation solution growth technique. From FT-IR and FT-RAMAN, the functional and vibrational frequencies of the grown crystals are assigned,
Mar 22,2022 Chemical ReagentsUses and Synthesis of Meldrum’s acid
Meldrum’s acid has attracted considerable attention due to its high acidity (pKa = 4.97) and rigid cyclic structure. Acylated derivatives (synthetic equivalents of mixed ketenes) readily undergo alcoh
Mar 22,2022 Chemical Reagents









