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100938-11-2

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100938-11-2 Structure

100938-11-2 Structure
IdentificationBack Directory
[Name]

ATRACTYLOSIDE SODIUM SALT
[CAS]

100938-11-2
[Synonyms]

Atraotydin
ATRACTYLOSIDE
SodiuM Atractylate
PubChem ID: 51346139
ATRACTYLOSIDE SODIUM
Atractylin SodiuM Salt
ATRACTYLOSIDE SODIUM SALT
Atractyloside DisodiuM Salt
Atractylic Acid DisodiuM Salt
ATRACTYLOSIDE SODIUM SALT USP/EP/BP
Atractyloside Disodium Salt Discontinued
ATRACTYLOSIDE SODIUM SALT FROM ATRACTYLIS GUMMIFERA
Atractyloside Disodium Salt Discontinued See A794540
(2β,4α,15α)-15-Hydroxy-2-[[2-O-(3-Methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic Acid DisodiuM Salt
(2beta,4alpha,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid disodium salt
[Molecular Formula]

C30H44Na2O16S2
[MDL Number]

MFCD00171231
[MOL File]

100938-11-2.mol
[Molecular Weight]

770.77
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H331-H311-H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
[Hazard Codes ]

T
[Risk Statements ]

23/24/25
[Safety Statements ]

36/37/39-45
[RIDADR ]

3172
[HazardClass ]

6.1(a)
[PackingGroup ]

I
Hazard InformationBack Directory
[Chemical Properties]

ATRACTYLOSIDE SODIUM SALT is White Solid
[Uses]

A specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in p ermeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. ATRACTYLOSIDE SODIUM SALT induces the release of ahyaluronidase-induced murine WW domain-containing oxidore ductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity.
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