| Identification | More | [Name]
Basic Orange 14 | [CAS]
10127-02-3 | [Synonyms]
3,6-ACRIDINEDIAMINE WITH ZINC CHLORIDE
3,6-BIS(DIMETHYLAMINO)ACRIDINE HEMIZINC CHLORIDE
3,6-BIS[DIMETHYLAMINO]ACRIDINE HEMI[ZINC CHLORIDE] SALT
3,6-BIS(DIMETHYLAMINO)ACRIDINE HYDROCHLORIDE ZINC CHLORIDE DOUBLE SALT
3,6-BIS(DIMETHYLAMINO)ACRIDINIUM CHLORIDE HEMI(ZINC CHLORIDE SALT)
ACRIDINE BRILLIANT ORANGE
ACRIDINE ORANGE
ACRIDINE ORANGE BIOLOGICAL STAIN
ACRIDINE ORANGE HEMI(ZINC CHLORIDE) SALT
ACRIDINE ORANGE, HEMIZINC SALT
ACRIDINE ORANGE-ZINC CHLORIDE COMPLEX
ACRIDINE ORANGE ZINC CHLORIDE DOUBLE SALT
BASIC ORANGE 14
BASIC ORANGE 3RN
CI 46005
CI 46025
CI NO 46005
EUCHRYSIN GNY
N,N,N',N'-tetramethylacridine-3,6-diamine monohydrochloride, compound with zinc dichloride
ACRIDINE ORANGE HEMI(ZINC CHLORIDE) | [EINECS(EC#)]
200-614-0 | [Molecular Formula]
C34H40Cl4N6Zn | [MDL Number]
MFCD00081043 | [Molecular Weight]
739.92 | [MOL File]
10127-02-3.mol |
| Chemical Properties | Back Directory | [Appearance]
brown powder | [Melting point ]
165 °C
| [storage temp. ]
Store at RT. | [solubility ]
H2O: soluble1mg/mL, clear, orange to very deep orange | [Colour Index ]
46005 | [form ]
Solid | [pka]
pKa -3.3(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);0.2(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);10.1(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain) | [color ]
Red brown | [PH]
3.9 (10g/l, H2O, 20℃) | [Stability:]
Stable. Incompatible with strong oxidizing agents. Protect from moisture. Hygroscopic. | [Water Solubility ]
soluble | [Sensitive ]
Hygroscopic | [BRN ]
3734978 | [CAS DataBase Reference]
10127-02-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R68:Possible risk of irreversible effects.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
AR7600000 | [HS Code ]
32041300 | [Toxicity]
A dye used to stain nucleic
acids. It fluoresces at 530 nm when intercalated into double
stranded DNA, or at 640 nm when ionically bound to single
stranded DNA. It produces mutations, some involving reading
frame shifts, other deletions or insertions and is carcinogenic.
It is also known to be a dermal phototoxicant. |
| Hazard Information | Back Directory | [Chemical Properties]
brown powder | [Uses]
Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase. | [General Description]
Acridine orange is a metachromatic fluorescent cationic dye that permeates the cell membrane and intercalates DNA and RNA. It allows for visual detection of nucleic acids on agarose and polyacrylamide gels. | [Biochem/physiol Actions]
Acridine orange (AO) is a fluorescent dye with two different staining characteristics. In fixed tissues, it acts as a metachromatic dye and differentially stains DNA (green) and RNA (orange). But, in living cells it acts as a pH indicator and produce brilliant orange-red in acidic condition. AO has been used to identify apoptotic cells in drosophila embryos. Acridine Orange staining method has been used to deliver more consistent data in the micronucleus test. |
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