| Identification | Back Directory | [Name]
CC-122 | [CAS]
1015474-32-4 | [Synonyms]
CC-122
CS-2428
Avadomide
CC122;CC 122
CC122 (Avadomide)
Avadomide(CC-122)
AVADOMIDE;CC122;CC 122
Avadomide (Synonyms: CC 122)
3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)piperidine-2,6-dione
3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione
2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)- | [Molecular Formula]
C14H14N4O3 | [MDL Number]
MFCD29919294 | [MOL File]
1015474-32-4.mol | [Molecular Weight]
286.29 |
| Chemical Properties | Back Directory | [Melting point ]
> 270°C (dec.) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
10.66±0.40(Predicted) | [color ]
Pale Beige |
| Hazard Information | Back Directory | [Description]
3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione has been shown to treat Diffuse large B-cell lymphoma with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon, a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4. |
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