| Identification | Back Directory | [Name]
GSK2141795 | [CAS]
1047634-65-0 | [Synonyms]
GSK795
CS-1304
GSK2141795
Uprosertib
GSK 2141795C
Uprosertib(GSK2141795)
Uprosertib , GSK2141795C
Uprosertib (GSK-2141795,GSK795)
GSK2141795 (Uprosertib, GSK795)
Uprosertib, 98%, a potent and selective pan-Akt inhibitor
N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furancarboxamide
2-Furancarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)- | [Molecular Formula]
C18H16Cl2F2N4O2 | [MDL Number]
MFCD28144686 | [MOL File]
1047634-65-0.mol | [Molecular Weight]
429.25 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:45.33(Max Conc. mg/mL);105.6(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.33(Max Conc. mM)
Ethanol:85.0(Max Conc. mg/mL);198.02(Max Conc. mM) | [form ]
Powder | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Uprosertib is a potent and selective inhibitor of pan-Akt (1). Serine/threonine protein kinases, such as Akt, play important roles in cellular activities including cell survival and apoptosis. |
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