Identification | Back Directory | [Name]
HUMAN ONCOSTATIN M | [CAS]
106956-32-5 | [Synonyms]
OSM RHOSM HUMAN OSM REC OSM (HUMAN) HUMAN ONCOSTATIN M ONCOSTATIN M, HUMAN Oncostatin-M from rat oncostatin m from mouse REC ONCOSTATIN M (HUMAN) Oncostatin M (209 aa) human RECOMBINANT HUMAN ONCOSTATIN M ONCOSTATIN M, HUMAN, RECOMBINANT ONCOSTATIN M (OSM), HUMAN, RECOMBINANT ONCOSTATIN M HUMAN RECOMBINANT CELL*CULT URE TESTED ONCOSTATIN M, MOUSE RECOMBINANT,*EXPRESS ED IN E. CO Oncostatin M (209aa), Human, recombinant, Animal-derived-free Oncostatin M human OSM, recombinant, expressed in HEK 293 cells, HumanKine(R), suitable for cell culture | [EINECS(EC#)]
200-835-2 | [Molecular Formula]
C62H86N12O16 | [MDL Number]
MFCD00166731 |
Hazard Information | Back Directory | [Uses]
Human oncostatin-M has been used to stimulate bovine full-depth cartilage explants. It has also been used to culture embryonic stem cells in standard minimum essential medium-α. | [General Description]
Oncostatin M (OSM) is produced by activated T cells, monocytes and Kaposi′s sarcoma cells. OSM shares several structural and functional characteristics with leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and ciliary neurotrophic factor (CNTF). | [Biochem/physiol Actions]
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. It can exert both stimulatory and inhibitory effects on cell proliferation. OSM stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi′s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release [e.g. interleukin-6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte-colony-stimulating factor (G-CSF)] from endothelial cells. |
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Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Website: |
https://www.sigmaaldrich.cn |
Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
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