ChemicalBook--->CAS DataBase List--->106956-32-5

106956-32-5

106956-32-5 Structure

106956-32-5 Structure
IdentificationBack Directory
[Name]

HUMAN ONCOSTATIN M
[CAS]

106956-32-5
[Synonyms]

OSM
RHOSM
HUMAN OSM
REC OSM (HUMAN)
HUMAN ONCOSTATIN M
ONCOSTATIN M, HUMAN
Oncostatin-M from rat
oncostatin m from mouse
REC ONCOSTATIN M (HUMAN)
Oncostatin M (209 aa) human
RECOMBINANT HUMAN ONCOSTATIN M
ONCOSTATIN M, HUMAN, RECOMBINANT
ONCOSTATIN M (OSM), HUMAN, RECOMBINANT
ONCOSTATIN M HUMAN RECOMBINANT CELL*CULT URE TESTED
ONCOSTATIN M, MOUSE RECOMBINANT,*EXPRESS ED IN E. CO
Oncostatin M (209aa), Human, recombinant, Animal-derived-free
Oncostatin M human OSM, recombinant, expressed in HEK 293 cells, HumanKine(R), suitable for cell culture
[EINECS(EC#)]

200-835-2
[Molecular Formula]

C62H86N12O16
[MDL Number]

MFCD00166731
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

lyophilized powder
[color ]

white to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H319-H332
[Precautionary statements ]

P305+P351+P338
[Hazard Codes ]

F,Xn
[Risk Statements ]

11-20/21/22-36
[Safety Statements ]

16-36/37
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Human oncostatin-M has been used to stimulate bovine full-depth cartilage explants. It has also been used to culture embryonic stem cells in standard minimum essential medium-α.
[General Description]

Oncostatin M (OSM) is produced by activated T cells, monocytes and Kaposi′s sarcoma cells. OSM shares several structural and functional characteristics with leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and ciliary neurotrophic factor (CNTF).
[Biochem/physiol Actions]

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. It can exert both stimulatory and inhibitory effects on cell proliferation. OSM stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi′s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release [e.g. interleukin-6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte-colony-stimulating factor (G-CSF)] from endothelial cells.
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