| Identification | Back Directory | [Name]
SAR131675 | [CAS]
1092538-80-1 | [Synonyms]
2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide | [Molecular Formula]
C18H22N4O4 | [MOL File]
1092538-80-1.mol | [Molecular Weight]
358.39 |
| Hazard Information | Back Directory | [Uses]
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the prolife
ration of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. | [Uses]
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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