| Identification | Back Directory | [Name]
WAY100635 | [CAS]
1092679-51-0 | [Synonyms]
CS-998
WAY100635 100MG
WAY100635 USP/EP/BP
Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
WAY-100635 (maleate) N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate | [Molecular Formula]
C25H34N4O2.C4H4O4 | [MOL File]
1092679-51-0.mol | [Molecular Weight]
538.635 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
≥53.9 mg/mL in DMSO; ≥51.2 mg/mL in EtOH; ≥6.08 mg/mL in H2O with ultrasonic | [form ]
solid | [Water Solubility ]
Soluble to 25 mM in water |
| Hazard Information | Back Directory | [Description]
WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and function of 5-HT1A receptors. However, WAY-100635 has also been shown to exhibit agonist activity at dopamine D4 receptors (Kd = 2.4 nM). | [storage]
Store at -20°C |
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