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ChemicalBook--->CAS DataBase List--->1094048-77-7

1094048-77-7

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1094048-77-7 Structure

1094048-77-7 Structure
IdentificationBack Directory
[Name]

I-OME-AG 538
[CAS]

1094048-77-7
[Synonyms]

I-OME-AG 538
I-OME-TYRPHOSTIN AG 538
TYRPHOSTIN I-OME-AG 538
α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone
ALPHA-CYANO-(3-METHOXY-4-HYDROXY-5-IODOCINNAMOYL)-(3',4'-DIHYDROXYPHENYL)KETONE
I-OMe-AG 538, α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3μ,4μ-dihydroxyphenyl)ketone
[Molecular Formula]

C17H12INO5
[MDL Number]

MFCD03453582
[MOL File]

1094048-77-7.mol
[Molecular Weight]

437.19
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO : 50 mg/mL (114.37 mM; Need ultrasonic)
[form ]

solid
[color ]

Yellow to orange
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.
[Definition]

ChEBI: 2-[(3,4-dihydroxyphenyl)-oxomethyl]-3-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-propenenitrile is a member of chalcones.
[Biochem/physiol Actions]

Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.
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