| Identification | Back Directory | [Name]
2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) | [CAS]
1165923-54-5 | [Synonyms]
GSK2262167
GSK-2262167
GSK 2262167
GSK-2262167 sodium
LCIDCFMLDWPFGR-UHFFFAOYSA-N
2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) | [Molecular Formula]
C25H27N4NaO4 | [MDL Number]
MFCD25977117 | [MOL File]
1165923-54-5.mol | [Molecular Weight]
470.5 |
| Hazard Information | Back Directory | [Description]
GSK-2262167 is a potent S1P3-sparing and orally active S1P1 agonist. CGSK-2262167 is as efficacious as fingolimod in a collagen-induced arthritis model and shows excellent pharmacokinetic properties preclinically. Importantly, the selectivity of GSK-2262167 against S1P3 is responsible for an absence of cardiovascular signal in telemetered rats, even at high dose levels. |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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