| Identification | Back Directory | [Name]
Alamandine | [CAS]
1176306-10-7 | [Synonyms]
Alamandine
Angiotensin A (1-7)
Angiotensin A (1-7) trifluoroacetate salt H-Ala-Arg-Val-Tyr-Ile-His-Pro-OH trifluoroacetate salt | [Molecular Formula]
C40H62N12O9 | [MOL File]
1176306-10-7.mol | [Molecular Weight]
855 |
| Chemical Properties | Back Directory | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
3.28±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: Alamandine is a peptide. | [Biochem/physiol Actions]
Alamandine is an endogenous heptapeptide that can be formed from angiotensin A by angiotensin converting enzyme-2 or directly from angiotensin-(1–7) by decarboxylation of its aspartate residue. Alamandine′s activity is similar to Ang-(1–7) rather than that of angiotensin II or angiotensin A. However, Alamandine acts at a different receptor, the Mas-related receptor, MrgD. Alamandine causes vasodilation, and has antifibrosis and antihypertensive activity. | [storage]
Store at -20°C |
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Sigma-Aldrich
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