| Identification | Back Directory | [Name]
Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- | [CAS]
1206881-47-1 | [Synonyms]
Armeniaspirol A
Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- | [Molecular Formula]
C18H19Cl2NO4 | [MOL File]
1206881-47-1.mol | [Molecular Weight]
384.25 |
| Hazard Information | Back Directory | [Description]
Armeniaspirols, a novel class of natural products isolated from Streptomyces armeniacus, have been previously identified as antibacterial agents against Gram-positive pathogens. Studies found that armeniaspirol A (ARM1) exhibited potent antibacterial activity against H. pylori, including multidrug-resistant strains, with MIC range values of 4-16 μg ml-1 . The underlying mechanism of action of ARM1 against H. pylori involved the disruption of bacterial cell membranes. |
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