1206881-47-1
英文名称
Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)-
CAS
1206881-47-1
分子式
C18H19Cl2NO4
分子量
384.25
MOL 文件
1206881-47-1.mol
![1206881-47-1 结构式](/CAS/20211123/GIF/1206881-47-1.gif)
基本信息
英文别名
Armeniaspirol ASpiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)-
应用领域
用途一
Armeniaspirols, a novel class of natural products isolated from Streptomyces armeniacus, have been previously identified as antibacterial agents against Gram-positive pathogens. Studies found that armeniaspirol A (ARM1) exhibited potent antibacterial activity against H. pylori, including multidrug-resistant strains, with MIC range values of 4-16 μg ml-1 . The underlying mechanism of action of ARM1 against H. pylori involved the disruption of bacterial cell membranes.