1206881-47-1

英文名称 Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)-

CAS 1206881-47-1

分子式 C18H19Cl2NO4

分子量 384.25

MOL 文件 1206881-47-1.mol

1206881-47-1 结构式

基本信息应用领域

基本信息

英文别名

Armeniaspirol A
Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)-

应用领域

用途一

Armeniaspirols, a novel class of natural products isolated from Streptomyces armeniacus, have been previously identified as antibacterial agents against Gram-positive pathogens. Studies found that armeniaspirol A (ARM1) exhibited potent antibacterial activity against H. pylori, including multidrug-resistant strains, with MIC range values of 4-16 μg ml-1 . The underlying mechanism of action of ARM1 against H. pylori involved the disruption of bacterial cell membranes.