| Identification | Back Directory | [Name]
FPL 64176 | [CAS]
120934-96-5 | [Synonyms]
FPL 64176
ARC-64176
MDMWHKZANMNXTF-UHFFFAOYSA-N
FPL 64176 >94% POTENT CA2+ CHANNEL (
Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate
2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester
4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester
2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER
2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER
1H-Pyrrole-3-carboxylic acid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester | [Molecular Formula]
C22H21NO3 | [MDL Number]
MFCD00274043 | [MOL File]
120934-96-5.mol | [Molecular Weight]
347.41 |
| Hazard Information | Back Directory | [Uses]
FPL-64176 is a nondihydropyridine Ca2+ channel activator. | [Definition]
ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester. | [Biological Activity]
Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria. | [Biochem/physiol Actions]
Potent Ca2+ channel (L-type) activator. | [storage]
Store at RT |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|