| Identification | More | [Name]
GALAXOLIDE | [CAS]
1222-05-5 | [Synonyms]
1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYLCYCLOPENTA[G]-2-BENZOPYRAN
1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYL-CYCLOPENTA-GAMMA-2-BENZOPYRAN
ABBALIDE
GALAXOLIDE
GALAXOLIDE 50
GALAXOLIDE 50 BB
GALAXOLIDE 50 IPM
HHCB
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta(g)-2-benzopyra
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta[g]-2-benzopyra
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno(5,6
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno(5,6-c)pyran
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene
Galoxolide
Musk50
Pearlide
HEXAMETHYLINDANOPYRAN
Hexahydro-4,6,6,7,8,8-hexamethyl cyclopenta-γ-2-benzopyran
Cyclopentag-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl- | [EINECS(EC#)]
214-946-9 | [Molecular Formula]
C18H26O | [MDL Number]
MFCD00217003 | [Molecular Weight]
258.4 | [MOL File]
1222-05-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
57-58° | [Boiling point ]
304 °C(lit.) | [density ]
1.044 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.073Pa at 25℃ | [refractive index ]
n20/D 1.5215(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
clear liquid | [color ]
Colorless to Light yellow | [Odor]
at 100.00 %. strong diffusive sweet floral musk | [Odor Type]
musk | [Water Solubility ]
1.65mg/L at 25℃ | [LogP]
5.3 at 25℃ | [CAS DataBase Reference]
1222-05-5(CAS DataBase Reference) | [EPA Substance Registry System]
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (1222-05-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R38:Irritating to the skin. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 3082 9 / PGIII | [WGK Germany ]
3
| [HS Code ]
2932.99.7000 | [HazardClass ]
9 | [PackingGroup ]
III | [Hazardous Substances Data]
1222-05-5(Hazardous Substances Data) | [Toxicity]
LD50 skin in rat: > 5gm/kg |
| Hazard Information | Back Directory | [Chemical Properties]
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]benzopyran is a viscous liquid with
a musk-like odor. It is one of the most frequently used synthetic, artificial musk
fragrances.The starting material for its synthesis is 1,1,2,3,3-pentamethylindane,
which is prepared by cycloaddition of tert-amylene to α-methylstyrene. The
pentamethylindane is hydroxyalkylated with propylene oxide in a Friedel–Crafts
reaction using aluminum chloride as a catalyst (analogous to the synthesis
of phenylethyl alcohol from benzene and ethylene oxide . Ring
closure of the resulting 1,1,2,3,3-pentamethyl-5-(β-hydroxyisopropyl)indane
is accomplished with paraformaldehyde and a lower aliphatic alcohol via the
acetal or with paraformaldehyde and a carboxylic acid anhydride via the
acylate.
The commercial product is diluted with solvents (e.g., diethyl phthalate, isopropyl
myristate, benzyl benzoate) to make it less viscous. It is alkali-stable and does not
discolor in light. Therefore, it is a popular ingredient of perfume compositions for
soaps, detergents, and cosmetics and is used in large amounts. | [Chemical Properties]
Clear Colourless to Pale Yellow Oil | [Uses]
Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents. | [Definition]
ChEBI: An organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively. It is a synthetic musk used as a fragrance in cosmetics. | [General Description]
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran is an isochromone with a strong musk odor, commonly used in fragrances. | [Flammability and Explosibility]
Notclassified | [Trade name]
Galaxolide® (IFF), Astromusk (Agan),Musk YingHai (YingHai). |
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