| Identification | Back Directory | [Name]
ML167 | [CAS]
1285702-20-6 | [Synonyms]
ML167
CS-1892
NCGC00188654
ML167/ML-167
CID 44968231
ML167 USP/EP/BP
ML167 >=98% (HPLC)
CID44968231;NCGC00188654
ML167; ML-167; ML 167; CID 44968231
5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol
(5-(4-(((5-Methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol
5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol ML167 | [EINECS(EC#)]
808-432-9 | [Molecular Formula]
C19H17N3O3 | [MDL Number]
MFCD27978379 | [MOL File]
1285702-20-6.mol | [Molecular Weight]
335.36 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble10mg/mL, clear | [form ]
powder | [color ]
off-white to gray to brown | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| Hazard Information | Back Directory | [Description]
ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50?= 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM). | [Definition]
ChEBI: [5-[4-[(5-methyl-2-furanyl)methylamino]-6-quinazolinyl]-2-furanyl]methanol is a member of quinazolines. | [target]
Clk4 | [References]
1) Rosenthal?et al. (2010),?An inhibitor of the Cdc2-like kinase 4 (Clk4); Probe Reports from the NIH Molecular Libraries Program |
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