Log in | Join Free | china | japan | germany
ChemicalBook--->CAS DataBase List--->134865-70-6

134865-70-6

Request For Quotation
134865-70-6 Structure

134865-70-6 Structure
IdentificationBack Directory
[Name]

8-M-PDOT
[CAS]

134865-70-6
[Synonyms]

AH 002
8-M-PDOT
8-METHOXY-2-PROPIONAMIDOTETRALIN
[Molecular Formula]

C14H19NO2
[MDL Number]

MFCD00901636
[MOL File]

134865-70-6.mol
[Molecular Weight]

233.31
Chemical PropertiesBack Directory
[Boiling point ]

447.8±45.0 °C(Predicted)
[density ]

1.09±0.1 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

Soluble to 50 mM in ethanol and to 100 mM in DMSO
[form ]

Powder
[pka]

15.87±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM). It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson''s disease.
[Uses]

AH 002 is a selective melatonin receptor agonist.
[Biological Activity]

Melatonin receptor agonist, 20-fold selective for the MT 2 (vs MT 1 ) subtype. At human recombinant MT 1 and MT 2 receptors, displays pK i values of 8.23 and 8.95 respectively.
134865-70-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Website: https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Website: www.emmx.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Website: www.chemegen.com
Company Name: Guangzhou Younan Technology Co., Ltd  
Tel: 020-020-82000279 18988968278
Website: www.ubiochem.cn/
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 15801484223;
Website: http://www.jm-bio.com/
Company Name: Shanghai Universal Biotech Co.,Ltd  
Tel: 18768175414
Website: https://www.univ-bio.com/
Company Name: Kaifeng Mingren Pharmaceutical Co.,LTD  
Tel: 0371-65741762
Website: www.kfmryy.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Tel: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: ApexBio Technology  
Tel: + 1-832-696-8203
Website: www.apexbt.com
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Website: www.caymanchem.com
Company Name: United States Biological  
Tel: 800.520.3011 or 781.639.5092
Website: www.usbio.net
Company Name: MedChemExpress  
Tel: 021-58955995
Website: www.medchemexpress.com
Company Name: Shanghai Hao Biological Technology Co., Ltd.  
Tel: 021-58116080 18019263206
Website: www.xiyuan-bio.com
Company Name: Shanghai Yihui Biotechnology Co., Ltd.  
Tel: 021-62962298
Website: www.yihbio.com
Tags:134865-70-6 Related Product Information