| Identification | Back Directory | [Name]
K811 | [CAS]
1355228-38-4 | [Synonyms]
K811
3-Quinolinecarboxamide, N-[4-[(6,7-dimethoxy-4-cinnolinyl)oxy]phenyl]-1,4-dihydro-1-(1-methylethyl)-4-oxo- | [Molecular Formula]
C29H26N4O5 | [MDL Number]
MFCD32697116 | [MOL File]
1355228-38-4.mol | [Molecular Weight]
510.54 |
| Hazard Information | Back Directory | [Description]
K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers. |
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