Identification | Back Directory | [Name]
ERK2 | [CAS]
137632-08-7 | [Synonyms]
ERK2 ERT1 MAPK1 PRKM1 PRKM2 MAP KINASE 2 Human MAPK1 Protein, GST Tag MAP Kinase Activated from rat Mitogen activated protein kinase Mitogen-activated protein kinase 1 Extracellular-signal regulated kinase Extracellular signal-regulated kinase 2 Extracellular signal- regulated kinase 2 RAB 3 RAT BRAIN RECOMBINANT & Mitogen activated protein kinase from rat Anti-P42 MAPK antibody produced in rabbit MAP KINASE, NON-ACTIVATED (RAT, RECOMBIN ANT) MONOCLONAL ANTI-ERK2 antibody produced in mouse MAP Kinase, N-terminal histidine-tagged non-activated protein map kinase, n-terminal histidine-tagged non-activated protein from rat | [MDL Number]
MFCD00677284 |
Hazard Information | Back Directory | [Biochem/physiol Actions]
MAP kinase is a serine/threonine kinase that is activated by MEK through a phosphorylation cascade. The cascade starts with extracellular signals transmitted by growth factor-regulated receptor tyrosine kinases or G-protein coupled receptors. Dually phosphorylated (Thr and Tyr) MAP kinase translocates from the cytoplasm to the nucleus, where it phosphorylates protein transcription factors, transducing extracellular signals into genomic responses, proliferation or differentiation. |
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