ChemicalBook--->CAS DataBase List--->138-37-4

138-37-4

138-37-4 Structure

138-37-4 Structure
IdentificationMore
[Name]

Mafenide hydrochloride
[CAS]

138-37-4
[Synonyms]

4-AMINOMETHYLBENZENESULFONAMIDE HYDROCHLORIDE
4-AMINOMETHYLBENZENESULFONAMINDE HYDROCHLORIDE
4-HOMOSULFANILAMIDE HYDROCHLORIDE
A-AMINO-P-TOLUENESULFONAMIDE HYDROCHLORIDE
ALPHA-AMINO-P-TOLUENESULFONAMIDE HYDROCHLORIDE
HOMOSULFAMINE HYDROCHLORIDE
LABOTEST-BB LT00454465
LABOTEST-BB LTBB000725
MAFENIDE
MAFENIDE HYDROCHLORIDE
MARFANIL
MARFANIL HYDROCHLORIDE
P-AMINOMETHYLBENZENE SULFONAMIDE HCL
P-AMINOMETHYLBENZENESULFONAMIDE HYDROCHLORIDE
alpha-amino-p-toluenesulfonamidmonohydrochloride
homosulfanilamidehydrochloride
masudin
morfanil
p-aminomethylphenylsulfonamidehydrochloride
sulfamylonhydrochloride
[EINECS(EC#)]

205-325-3
[Molecular Formula]

C7H11ClN2O2S
[MDL Number]

MFCD00013005
[Molecular Weight]

222.69
[MOL File]

138-37-4.mol
Chemical PropertiesBack Directory
[Melting point ]

261-263 °C(lit.)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

neat
[color ]

White
[Merck ]

13,5671
[InChIKey]

SIACJRVYIPXFKS-UHFFFAOYSA-N
[CAS DataBase Reference]

138-37-4(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R42/43:May cause sensitization by inhalation and skin contact .
[Safety Statements ]

S22:Do not breathe dust .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[WGK Germany ]

2
[RTECS ]

XT5425000
[HS Code ]

29350090
[Toxicity]

LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Hydrochloric acid-->Ethyl acetate-->Sulfuric acid-->Dichloromethane-->Chloroform-->Triethylamine-->Ammonia-->Acetyl chloride-->Chlorosulfonic acid-->Benzylamine
Hazard InformationBack Directory
[Uses]

Antibacterial;Inhibitor of folic acid biosynthesis
[storage]

Store at -20°C
[Purification Methods]

Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.]
Spectrum DetailBack Directory
[Spectrum Detail]

Mafenide hydrochloride(138-37-4)MS
Mafenide hydrochloride(138-37-4)1HNMR
Mafenide hydrochloride(138-37-4)13CNMR
Mafenide hydrochloride(138-37-4)IR1
Mafenide hydrochloride(138-37-4)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

138-37-4(sigmaaldrich)
[TCI AMERICA]

Homosulfamine Hydrochloride,>98.0%(T)(138-37-4)
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