ChemicalBook--->CAS DataBase List--->141942-85-0

141942-85-0

141942-85-0 Structure

141942-85-0 Structure
IdentificationMore
[Name]

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
[CAS]

141942-85-0
[Synonyms]

ATS-5
BUTANOIC ACID, 4-CYANO-3-HYDROXY-, ETHYL ESTER, (R)
BUTANOIC ACID 4-CYANO-3-HYDROXY-ETHYL ESTER, (S)
ETHYL (3R)-4-CYANO-3-HYDROXY-BUTANOATE
ETHYL (R)-4-CYANO-3-HYDROXYBUTANOATE
ETHYL-(R)-(+)-4-CYANO-3-HYDROXYBUTANOATE
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
ETHYL (R)-(-)-4-CYANO-3-HYDROXYBUTYRATE
ETHYL (R)-4-CYANO-3-HYDROXYBUTYRATE
ETHYL (S)-4-CYANO-3-HYDROXYBUTANOATE
ETHYL (S)-(+)-4-CYANO-3-HYDROXYBUTYRATE
ETHYL(S)-4-CYANO-3-HYDROXY-BUTYRATE
(R)-(-)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER
(R)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER
(R)-(-)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE
(R)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE
(S)-4-CYANO-3-HYDROXYBUTANOATE ETHYL
(S)-ETHYL-4-CYANO-3-HYDROXYBUTYRATE
(R)-4-Cyano-3-hydroxy butanoate
(R)-4-cyano-3-hydroxybutyric
[EINECS(EC#)]

430-220-6
[Molecular Formula]

C7H11NO3
[MDL Number]

MFCD00672878
[Molecular Weight]

157.17
[MOL File]

141942-85-0.mol
Chemical PropertiesBack Directory
[Appearance]

yellow liquid
[alpha ]

-5 º (neat)
[Boiling point ]

270 °C(lit.)
[density ]

1.114 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.448(lit.)
[Fp ]

>230 °F
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
[form ]

Liquid
[pka]

13.03±0.20(Predicted)
[color ]

Colorless to yellow
[Specific Gravity]

1.114
[optical activity]

[α]25/D 5°, neat
[BRN ]

5328715
[InChIKey]

LOQFROBMBSKWQY-ZCFIWIBFSA-N
[CAS DataBase Reference]

141942-85-0(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

1
[HS Code ]

29269090
Questions And Answer(Q&A)Back Directory
[Application]

Hydroxyglutaryl coenzyme A (HMG-CoA) reductase inhibitors are a new class of lipid-lowering drugs, and they have a market share of more than 10 billion US dollars in the current pharmaceutical field. They can selectively inhibit the rate-limiting enzyme HMG-CoA reductase in cholesterol synthesis in the liver, reduce liver lipoprotein production, and increase the expression of low-density lipoprotein (LDL) cholesterol receptors, thereby reducing plasma cholesterol levels. They can also significantly reduce very low-density lipoprotein (VLDL) and triglycerides, and increase anti-atherosclerotic high-density protein (HDL), preventing atherosclerosis and coronary heart disease.
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate is an important intermediate for the synthesis of HMG-CoA reductase inhibitors. If it is used as a raw material, synthetic atorvastatin is mainly used for the treatment of hypercholesterolemia and mixed hyperlipidemia, coronary heart disease and stroke.
Hazard InformationBack Directory
[Chemical Properties]

yellow liquid
[Uses]

analgesic, antipyretic, and anti-inflammatory
[Uses]

Atorvastatin Intermediate
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, 98%(141942-85-0)
[TCI AMERICA]

Ethyl (R)-(-)-4-Cyano-3-hydroxybutyrate,>97.0%(GC)(141942-85-0)
141942-85-0 suppliers list
Company Name: Jiangxi Sunway Chemical Co., Ltd.
Tel: +86-0794-5259909 +8615888611133 , +8615888611133
Website: www.jxswchem.com
Company Name: Hebei Mujin Biotechnology Co.,Ltd
Tel: +86 13288715578 +8613288715578 , +8613288715578
Website: http://www.mojinchemical.com
Company Name: Hebei Chuanghai Biotechnology Co,.LTD
Tel: +86-13131129325 , +86-13131129325
Website: www.chuanghaibio.com
Company Name: Hebei Dangtong Import and export Co LTD
Tel: +86-86-4001020630 +8619831957301 , +8619831957301
Website: www.chemicalbook.com/showsupplierproductslist609684/0.htm
Company Name: Hangzhou ICH Biofarm Co., Ltd
Tel: +86-0571-28186870; +undefined8613073685410 , +undefined8613073685410
Website: http://www.ichemie.com/
Company Name: hebei hongtan Biotechnology Co., Ltd
Tel: +852-6619 3215 +86-17731935328 , +86-17731935328
Website: hbht123.com
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-(0)57185586718 +86-13336195806 , +86-13336195806
Website: www.capot.com
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-+86-371-66670886
Website: www.dakenchem.com/
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: Hubei XinRunde Chemical Co., Ltd.
Tel: +8615102730682
Website: www.chemicalbook.com/ShowSupplierProductsList30595/0_EN.htm
Company Name: Zjartschem
Tel: +86-571 87238903
Website: www.zjartschem.com/eacpzs.asp?dlb_id=12
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: NINGBO INNO PHARMCHEM CO., LTD.
Tel: 13867897135
Website: en.nbinno.com
Company Name: Jinan Finer Chemical Co., Ltd
Tel: +86-531-88989536 +86-15508631887 , +86-15508631887
Website: www.finerchem.com
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86-86-5926051114 +8615060885618 , +8615060885618
Website: www.amoychem.com/
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.chemicalbook.com/ShowSupplierProductsList1549548/0.htm
Company Name: Shanghai Longyu Biotechnology Co., Ltd.
Tel: +8619521488211 , +8619521488211
Website: www.chemicalbook.com/manufacturer/shanghai-longyu-biotechnology-164/
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873 , +86-86-13650506873
Website: http://www.chemdad.com/
Tags:141942-85-0 Related Product Information
137234-87-8 141-78-6 148893-10-1 95266-40-3 110-80-5 6317-18-6 7085-85-0 109-94-4 105-54-4 623-49-4 64-17-5 5405-41-4 97-62-1 610-02-6 25895-60-7 120-47-8 125995-13-3 125971-94-0

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.