| Identification | Back Directory | [Name]
HC≡C-CH2-PEG6-SH | [CAS]
1422540-91-7 | [Synonyms]
HC≡C-CH2-PEG6-SH
Propargyl-PEG6-SH
3,6,9,12,15,18-hexaoxahenicos-20-yne-1-thiol
3,6,9,12,15,18-Hexaoxaheneicos-20-yne-1-thiol | [Molecular Formula]
C15H28O6S | [MDL Number]
MFCD31747071 | [MOL File]
1422540-91-7.mol | [Molecular Weight]
336.44 |
| Hazard Information | Back Directory | [Biological Activity]
Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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| Company Name: |
PurePEG，LLC
|
| Tel: |
1.858.408.4567 |
| Website: |
www.purepeg.com |
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