Identification | More | [Name]
5-Methyluridine | [CAS]
1463-10-1 | [Synonyms]
1-(BETA-D-RIBOFURANOSYL)THYMIDINE 1-(BETA-D-RIBOFURANOSYL)THYMINE 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL 5-METHYL-D-URIDINE 5-METHYLURIDINE BETA-D-THYMINE RIBOSIDE BETA-RIBOFURANOSIDE ribosylthymine RIBOTHYMIDINE 5-methyl-uridin 5-methyuridine 5-Methyluridine (Patent ) 5-METHYLURIDINE(5-Methyl-1-ˉ-ribofuranosyl uracil 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 5-methyluridine/ribothymidine ribosylthymine/5-methyluridine THYMINERIBOSIDE URIDINE, 5-METHYL- Methyluridine 1-β-D-Ribofuranosylthymine | [EINECS(EC#)]
215-973-9 | [Molecular Formula]
C10H14N2O6 | [MDL Number]
MFCD00006535 | [Molecular Weight]
258.23 | [MOL File]
1463-10-1.mol |
Chemical Properties | Back Directory | [Appearance]
White Powder | [Melting point ]
183-184 °C(lit.)
| [density ]
1.576±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated) | [form ]
powder
| [pka]
9.55±0.10(Predicted) | [color ]
white
| [InChI]
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1 | [InChIKey]
DWRXFEITVBNRMK-JXOAFFINSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O | [CAS DataBase Reference]
1463-10-1(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29349900 |
Hazard Information | Back Directory | [Description]
5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine. | [Chemical Properties]
White Powder | [Uses]
A primary degradation product of tRNA, | [Definition]
ChEBI: Ribothymidine is a methyluridine having a single methyl substituent at the 5-position on the uracil ring. It has a role as a human metabolite, an Escherichia coli metabolite and an antigen. | [storage]
Store at -20°C |
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