Identification | More | [Name]
4-(DIFLUOROMETHOXY)NITROBENZENE | [CAS]
1544-86-1 | [Synonyms]
1-(DIFLUOROMETHOXY)-4-NITROBENZENE 4-(DIFLUOROMETHOXY)NITROBENZENE 4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE BUTTPARK 45\10-48 Anisole,α,α-difluoro-p-nitro- Benzene,1-(difluoromethoxy)-4-nitro- Difluoromethyl4-nitrophenylether p-Nitrophenyldifluoromethylether α,α-Difluoro-p-nitroanisole 4-(Difluoromethoxy)nitrobenzen, 98% 4-(Difluoromethoxy)nitrobenzene98% | [Molecular Formula]
C7H5F2NO3 | [MDL Number]
MFCD00085009 | [Molecular Weight]
189.12 | [MOL File]
1544-86-1.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
3276 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29049090 |
Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Crystal. | [Uses]
4-(Difluoromethoxy)nitrobenzene is an industrial chemical that can be used to make 4-fluoro-3-pyridinol (F3P), a compound that has potential as a new drug for the treatment of cancer. The synthesis of F3P begins with the reaction of 4-(difluoromethoxy)nitrobenzene and potassium hydroxide in methanol, which yields 4-fluoro-3-hydroxypyridine. This product is then reacted with ammonia gas and pyridine to yield F3P. The final step involves heating the product at high temperature with nitric acid, which yields nitrobenztriazole. | [General Description]
4-(Difluoromethoxy)nitrobenzene (1-(difluoromethoxy)-4-nitrobenzene) can be synthesized by reacting 4-nitrophenol with KOH, water and methanol. |
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