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173943-29-8

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173943-29-8 Structure

173943-29-8 Structure
IdentificationBack Directory
[Name]

YM 44781
[CAS]

173943-29-8
[Synonyms]

YM44781
YM-44781
YM 44781
[Molecular Formula]

C31H32Cl2FN3O2
[MOL File]

173943-29-8.mol
[Molecular Weight]

568.51
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[Description]

YM44781 is a novel non-peptide tachykinin receptor antagonist. YM44781 exhibited high binding affinities at NK(2) (pK(i) = 9.94 +/- 0.03) and NK(1) (pK(i) = 9.09 +/- 0.02) receptors, respectively. _x000D_ YM-44781 did not produce major inhibition of [Sar9,Met(O(2))11]substance P-induced bladder contraction.
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