173943-29-8

英文名称 YM 44781

CAS 173943-29-8

分子式 C31H32Cl2FN3O2

分子量 568.51

MOL 文件 173943-29-8.mol

173943-29-8 结构式

基本信息应用领域

基本信息

英文别名

YM44781
YM-44781
YM 44781

应用领域

用途一

YM44781 is a novel non-peptide tachykinin receptor antagonist. YM44781 exhibited high binding affinities at NK(2) (pK(i) = 9.94 +/- 0.03) and NK(1) (pK(i) = 9.09 +/- 0.02) receptors, respectively. _x000D_ YM-44781 did not produce major inhibition of [Sar9,Met(O(2))11]substance P-induced bladder contraction.