ChemicalBook--->CAS DataBase List--->175033-36-0

175033-36-0

175033-36-0 Structure

175033-36-0 Structure
IdentificationBack Directory
[Name]

NO-ASPIRIN 1
[CAS]

175033-36-0
[Synonyms]

C102148
NCX 4016
NO-ASPIRIN 1
nitroaspirin
Nitric oxide-releasing aspirin
3-(NitroxyMethyl)phenyl 2-acetoxybenzoate
2-Acetoxybenzoate-2-(1-nitroxymethyl)phenyl ester
2-AcetyloxybenzoicAcid3-NitrooxymethylphenylEster
2-(ACETYLOXY)-3-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
[Molecular Formula]

C16H13NO7
[MDL Number]

MFCD00952953
[MOL File]

175033-36-0.mol
[Molecular Weight]

331.28
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

61-62°C
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly)
[form ]

powder
[color ]

white to beige
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

NO-Aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (NO) donor. It contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an NO-releasing moiety. It also prevents restinosiis, inhibits proliferation of vascular smooth muscle cells, reduces infarct ssize following cardiac ischemia, and exhibits strong chemopreventative effects against colon cancer development.
[Definition]

ChEBI: 2-acetyloxybenzoic acid [3-(nitrooxymethyl)phenyl] ester is a carbonyl compound.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

NO-ASPIRIN 1(175033-36-0)1HNMR
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