| Identification | More | [Name]
Benzenesulfonic acid | [CAS]
98-11-3 | [Synonyms]
BENZENESULFONIC ACID
BENZENESULPHONIC ACID
BL70
17-120a
acidebenzenesulfonique
Benzenemonosulfonic acid
benzenemonosulfonicacid
Benzenesulfonicacid(40%solu
Besylic acid
besylicacid
Kyselina benzensulfonova
kyselinabenzensulfonova
BENZENESULFONIC ACID 90% TECHNICAL GRADE
BENZENE SULFONIC ACID TECHNICAL GRADE
BENZOLSULFONSAEURE
BENZENESULFONIC ACID SOLUTION 70% IN WA
BENZENESULFONIC ACID, TECH., 90%
BENZENESULFONIC ACID SOLUTION 30-35%
BENZENESULFONIC ACID, 98+%
BENZENESULFONIC ACID,PRACTICAL GRADE 90-95% | [EINECS(EC#)]
202-638-7 | [Molecular Formula]
C6H6O3S | [MDL Number]
MFCD00011689 | [Molecular Weight]
158.18 | [MOL File]
98-11-3.mol |
| Chemical Properties | Back Directory | [Appearance]
green solid | [Melting point ]
30-60 °C | [Boiling point ]
137℃ | [density ]
1.32 | [vapor pressure ]
69.8Pa at 20℃ | [refractive index ]
1.5151 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
H2O: soluble0.1g/10 mL, clear, colorless | [form ]
Damp Crystalline Solid or Fused Mass | [pka]
0.7(at 25℃) | [color ]
Yellow to light brown | [PH]
2 (H2O, 20℃)(saturated solution) | [Stability:]
Stable. Incompatible with strong oxidizing agents, bases, many organic compounds. | [Water Solubility ]
soluble | [Sensitive ]
Hygroscopic | [Merck ]
14,1070 | [BRN ]
742513 | [InChIKey]
SRSXLGNVWSONIS-UHFFFAOYSA-N | [LogP]
0.41 at 25℃ | [CAS DataBase Reference]
98-11-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzenesulfonic acid(98-11-3) | [EPA Substance Registry System]
98-11-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 2583 8/PG 2
| [WGK Germany ]
1
| [RTECS ]
DB4200000
| [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29041000 | [Safety Profile]
Poison by ingestion,
sbn contact, and probably inhalation. A
severe skin and eye irritant. See also
SULFATES and SULFONATES. | [Hazardous Substances Data]
98-11-3(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 1175 mg/kg |
| Hazard Information | Back Directory | [General Description]
Deliquescent needles or large plates. | [Reactivity Profile]
BENZENESULFONIC ACID(98-11-3) reacts with bases and many organic compounds. | [Air & Water Reactions]
Slightly soluble in water. | [Fire Hazard]
Flash point data for this chemical are not available, however BENZENESULFONIC ACID is probably combustible. | [Description]
Benzene sulfonic acid is an organo sulfur compound with the formula C6H5SO3H. It is the simplest aromatic sulfonic acid. It forms colorless deliquescent sheet crystals or a white waxy solid that is soluble in water and ethanol, slightly soluble in benzene and insoluble in carbon disulfide and diethyl ether. It is often stored in the form of alkali metal salts. Its aqueous solution is strongly acidic. | [Chemical Properties]
green solid | [History]
Benzenesulfonic acid was first obtained, together with diphenyl sulfone, by E. M ITSCHERLICH in 1834 by heating benzene with fuming sulfuric acid. The industrially important reaction of benzenesulfonic acid with alkali hydroxide to form phenol (alkali fusion) was developed by A. WURTZ and A. KEKULé in 1867 and by P. O. D EGENER in 1878. Until the early 1960s benzenesulfonic acid was used chiefly in the manufacture of phenol. Other phenol syntheses are preferred now.
| [Uses]
Benzenesulfonic acid is mainly consumed by conversion to other specialty chemicals. A variety of pharmaceutical drugs are prepared as salts of benzenesulfonic acid and are known as besylates or besilates. The alkali metal salt of benzenesulfonic acid was once widely used in the production of phenol. It acts as an acid catalyst for direct esterification of amino acids and peptides. | [Application]
The alkali metal salt of benzene sulfonic acid was once widely used in the production of phenol :
C6H5SO3Na + 2 NaOH → C6H5ONa + Na2SO3
C6H5ONa + HCl → C6H5OH + NaCl
The process has been largely displaced by the Hock process, which generates less waste. Benzene sulfonic acid is mainly consumed by conversion to other specialty chemicals. A variety of pharmaceutical drugs are prepared as salts of benzene sulfonic acid and are known as besylates or besilates. | [Definition]
A white crystalline
acid made by sulfonation of benzene. Any
further substitution onto the benzene ring
is directed into the 3 position. | [Definition]
benzenesulphonic acid: A colourlessdeliquescent solid, C6H5SO2OH,m.p. 43–44°C, usually found as anoily liquid. It is made by treating benzenewith concentrated sulphuricacid. Its alkyl derivatives are used asdetergents. | [Definition]
ChEBI: The simplest member of the class of a benzenesulfonic acids that consists of a benzene carrying a single sulfo group. | [Preparation]
Benzene sulfonic acid is prepared from the sulfonation of benzene using concentrated sulfuric acid :
This conversion illustrates aromatic sulfonation, which has been called "one of the most important reactions in industrial organic chemistry.". | [Reactions]
Benzene sulfonic acid exhibits the reactions typical of other aromatic sulfonic acids, forming sulfonamides , sulfonyl chloride, and esters. The sulfonation is reversed above 220 °C. Dehydration with phosphorus pentoxide gives benzene sulfonic acid anhydride ((C6H5SO2)2O). Conversion to the corresponding benzene sulfonyl chloride (C6H5SO2Cl) is effected with phosphorus penta chloride. It is a strong acid, being dissociated in water. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 61, p. 1530, 1996 DOI: 10.1021/jo9520710
Tetrahedron Letters, 19, p. 1211, 1978 DOI: 10.1016/S0040-4039(01)94501-0 | [Flammability and Explosibility]
Nonflammable | [Purification Methods]
Purify benzenesulfonic acid by dissolving it in a small volume of distilled H2O and stirring with slightly less than the theoretical amount of BaCO3. When effervescence is complete and the solution is still acidic, filter off the insoluble barium benzenesulfonate. The salt is collected and dried to constant weight in vacuo, then suspended in H2O and stirred with a little less than the equivalent (half mol.) of sulfuric acid. The insoluble BaSO4 (containing a little barium benzenesulfonate) is filtered off and the filtrate containing the free acid is evaporated in a high vacuum. The oily residue will eventually crystallise when completely anhydrous. A 32% commercial acid is allowed to fractionally crystallise at room temperature over P2O5 in a vacuum desiccator giving finally colourless deliquescent plates m 52.5o. The anhydrous crystalline acid is deliquescent and should be stored over anhydrous Na2SO4 in the dark and should be used in subdued sunlight as it darkens under sunlight. The main impurity is Fe which readily separates as the Fe salt in the early fractions [Taylor & Vincent J Chem Soc 3218 1952]. The S-benzylisothiuronium salt has m 148o (from EtOH/H2O). It is an IRRITANT to the skin and eyes. [See Adams & Marvel Org Synth Coll Vol I 84 1941, Michael & Adair Chem Ber 10 585 1877, Beilstein 11 IV 27.] | [Waste Disposal]
Benzenesulfonic acid is biologically degradable. If the desired benzenesulfonic acid can be precipitated from sulfuric acid solution without salt being added, the spent acid can be upgraded in a sulfuric acid recovery plant. If the wastewater contains salts and nondegradable sulfonic acids, low-pressure wet oxidation is a possible method of treatment that subsequently allows effective degradation in wastewater treatment works. |
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